Dr Jacopo Branca

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Dr Jacopo Branca

 

Department of Experimental and Clinical Medicine at the University of Florence, Italy. Graduated in Cellular and Molecular Biology at University of Florence in 2012. Current research targets on the biological effects (cell viability and morphology, signal transduction pathways, angiogenesis) of heavy metals and the vitamin D axis - vitamin D, vitamin D receptor, vitamin D binding protein (Gc protein) and vitamin D binding protein-derived macrophage activating factor (GcMAF) - on different normal and transformed human and animal cells.

 

 

 

Effects of GcMAF on neuronal and glial cells.

 

Pollutants and other environmental stimuli are involved in the aetio-pathogenesis of a variety of diseases ranging from cancer to autism, chronic fatigue syndrome and other neurodegenerative diseases. In this study, we examined the effects of a new stabilized GcMAF molecule on human neurons and glial cells. Cell viability, cell morphology and VEGF expression are investigated before and after the treatment with GcMAF. The effects observed in vitro are consistent with those observed in the experimental animal and in clinical settings where the therapeutic effects of GcMAF in autism and neurodegenerative diseases have been demonstrated.