Dr Gabriele Morucci PhD

Dr Gabriele Morucci

Dr Gabriele Morucci is a postdoctoral researcher in the Department of Experimental and Clinical Medicine at the University of Florence, Italy. He gained his PhD in Human Morphology and Morphogenesis from the University of Florence in 2011. His current research focuses on the biological effects (cell viability and morphology, signal transduction pathways and angiogenesis) of the Vitamin D axis - Vitamin D, Vitamin D receptor, Vitamin D binding protein (Gc protein) and Vitamin D binding protein-derived macrophage activating factor (GcMAF) - on different normal and transformed human and animal cells.

 

Effects of GcMAF on neuronal and glial cells.


 

Pollutants and other environmental stimuli are involved in the aetio-pathogenesis of a variety of diseases ranging from cancer to autism, chronic fatigue syndrome and other neurodegenerative diseases. In this study, we examined the effects of a new stabilized GcMAF molecule on human neurons and glial cells. Cell viability, cell morphology and VEGF expression are investigated before and after the treatment with GcMAF. The effects observed in vitro are consistent with those observed in the experimental animal and in clinical settings where the therapeutic effects of GcMAF in autism and neurodegenerative diseases have been demonstrated